Medline Industries, one of the world’s largest medical-supplies companies, revealed an initial public offering filing in the U.S. that could value the firm at up to $50 billion. The firm posted a 9.7% revenue gain for the first half of 2025 and is backed by prominent private-equity investors. The IPO marks a meaningful moment for the global primary-markets revival, coming after years of muted listings and cautious investor sentiment. Market watchers say the deal’s timing and size signal improved conditions for large cap IPOs in healthcare and beyond.